Knull, God Of The Symbiotes Returns In ALL-NEW VENOM #250 This October

By Chad Burdette

on June 21, 2025

This past Monday was June 16, or otherwise known as 616 Day. To celebrate this momentous day, Marvel Comics announced that the landmark 250^th issue of VENOM hits stands in October and features the return of KNULL, Venom’s greatest enemy!

Related News and Reviews:

Written by current All-New Venom scribe Al Ewing and drawn by superstar artist Terry Dodson, VENOM #250 kicks off a major symbiote saga where Knull, the god of symbiotes, seeks revenge on Venom, who is currently bonded to Mary Jane Watson!

Debuting in Donny Cates and Ryan Stegman’s seminal run of Venom back in 2018, Knull immediately took a spot amongst Marvel’s most feared and legendary supervillains, going on to headline his own crossover event as the KING IN BLACK and even making his big screen debut in last year’s Venom: The Last Dance. Now, he’s back with a vengeance, and Mary Jane has no idea what’s in store!

On Knull’s appeal, Ewing said,

“When Donny and Ryan brought Knull into being, they created the first new villain in a while with what I’d call ‘big villain juice.’ He’s visually arresting, you know what he wants in one sentence, you can’t talk him out of it, he’s powerful enough to hold down a crossover… and he was given the wonderful luxury of going away for a while. When a big bad is allowed to lay fallow and drift into memory, what’s remembered is all the things readers liked about them – and that’s when it’s time for a comeback. The final ingredient in a good villain – they may be down, but they’re never out.”

The giant-sized celebratory issue will also feature a tale by Eddie Brock: Carnage writer Charles Soule and All-New Venom artist Carlos Gomez set during Eddie Brock’s time as Venom. Plus, following the issue, ALL-NEW VENOM remains VENOM once more, continuing on with the legacy numbering with VENOM #251!

VENOM #250

THE RETURN OF KNULL!

Mary Jane Watson is finally in the swing of things as the new Venom host, using their powers in all-new ways to be the hero the symbiote never knew it could be! But as she cleans up the streets of New York, she remains blissfully unaware of the strands of darkness leading off into the darkness of the void. Knull, the creator of all symbiotes, was killed by Eddie Brock. Nothing could bring him back… but Knull rules over nothing. Knull has returned, and word is racing across the stars to the one who took him down before to prepare to do it again. Will Venom be ready?

Creative Team